What is preimplantation genetic diagnosis?

Preimplantation genetic diagnosis (PGD) is a screening test used to determine if genetic or chromosomal disorders are present in embryos produced through in vitro fertilization (IVF). Preimplantation genetic diagnosis screens embryos before they are transferred to the uterus so couples can make informed decisions about their next steps in the IVF process. Embryos unaffected by the genetic or chromosomal disorder can be selected for transfer to the uterus.

For couples undergoing IVF, preimplantation genetic diagnosis may be recommended when:


~ One or both partners has a history of heritable genetic disorders


~ One or both partners is a carrier of a chromosomal abnormality


~ The mother is of advanced maternal age


~ The mother has a history of recurrent miscarriages


~ For couples with heritable genetic disorders


~ For couples with chromosomal disorders



Should I see a genetic counselor before undergoing pre-implantation genetic diagnosis?

Genetic counseling is an important step to determine if preimplantation genetic diagnosis is an appropriate option for a patient. Akruti Fertility Centre has its own full time genetic counsellor of Reproductive Genetics. For couples undergoing IVF who are concerned that their child may inherit a genetic disorder or chromosomal abnormality, genetic counsellor is available to discuss options and can advise patients .


What is the step–by–step process for preimplantation genetic diagnosis?

Preimplantation genetic diagnosis is available for couples undergoing IVF. The steps of the IVF process include:


~ Medications are used to suppress a woman's natural menstrual cycle.


~ Her ovaries are then stimulated with medications to produce multiple follicles, each of which may contain an oocyte (egg).


~ The eggs are retrieved from the woman's ovary by a needle placed in the vagina.


~In the lab, the eggs are combined with the male partner's sperm in a special culture medium that allows fertilization and the growth of high–quality embryos.


~ Embryo biopsy may be performed after 3 days of culture in the laboratory. The embryos are typically 8-cell embryos on Day-3 and the process involves the removal of one to two cells.


AKRUTI FERTILITY CENTRE DOES NOT CONDUCT ANY SEX SELECTION PROCEDURES.

SEX SELECTION IS BANNED IN INDIA AND IS A CRIMINAL OFFENCE WITH UPTO 3 YEARS IN JAIL

PGD / PGS

Preimplantation Genetic Diagnosis (Embryo Screening)

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